Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
OBJECTIVE The aetiology of systemic lupus erythematosus (SLE) is incompletely understood. Both genetic and environmental factors are implicated in the pathogenesis of the disease. Herein, we describe genetic association between SLE and polymorphisms in the interleukin (IL)-21 gene. The reported effect of IL-21 on B-cell differentiation into plasma cells and its effect on dendritic cell maturati...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2007
ISSN: 0003-4967,1468-2060
DOI: 10.1136/ard.2007.075424